Poison & Wine

Williams, White and their friend Chris Lindsey wrote it in Nashville, Lindsey being the only outside collaborator on the album. Interview Magazine says it draws on the idea that a relationship holds both affection and frustration. It first appeared live at Eddie's Attic, recorded April 8, 2009. The studio version was recorded at Peacock's Art House. When Grey's Anatomy used it in the ninth episode of season six in November 2009, the duo had no iTunes release or video and rushed both; Williams said everything felt like small hinges on a very large door. It debuted at 4 on iTunes' Singer/Songwriter chart, and the Poison & Wine EP followed. The video was made in an afternoon and was nominated for three CMT awards in 2012, for Video of the Year, Collaborative Video and Duo Video.

Songwriting teacher Robin Frederick describes alternating verse and refrain, no bridge, lines built on contradiction and negation, and three chords repeated with the middle note of each chord omitted, capo at the second fret. A 2011 long-distance YouTube cover by Juliana Richer Daily and Alex Cornell exists. We found no setlist counts, and do not know which performance our upload is.